Ticker Details
Spyre Therapeutics, Inc.
IPO Date:	April 4, 2016
Sector:	Healthcare
Industry:	Biotech
Market Cap:	$3.35B
Activated in VL:	True

Average Daily Range
Avg Daily Range:	$0.82 | 3.32%
Avg Daily Range (30 D):	$1.02 | 2.96%
Avg Daily Range (90 D):	$0.82 | 2.76%

Institutional Daily Volume
Avg Daily Volume:	.47M
Avg Daily Volume (30 D):	.55M
Avg Daily Volume (90 D):	.64M

Trade Size
Avg Trade Size (Sh.):	60
Avg Trade Size (Sh.) (30 D):	45
Avg Trade Size (Sh.) (90 D):	51

Institutional Trades
Total Institutional Trades:	1,072
Avg Institutional Trade:	$2.11M
Avg Institutional Trade (30 D):	$2.64M
Avg Institutional Trade (90 D):	$2.65M
Avg Institutional Trade Volume:	.08M
Avg Institutional Trades (Per Day):	2

Market Closing Trades
Avg Closing Trade:	$2.82M
Avg Closing Trade (30 D):	$3.55M
Avg Closing Trade (90 D):	$4.41M
Avg Closing Volume:	117.93K

News

Feb 23, 2026 @ 3:18 PM Spyre Therapeutics Stock Surges This Past Year as ... Source: Jonathan Ponciano

Jan 23, 2026 @ 9:00 PM Spyre Therapeutics Announces Grants of Inducement ... Source: Na

Jan 11, 2026 @ 2:17 PM Spyre Therapeutics' CEO Sells 15,000 Shares Source: Lawrence Rothman, Cfa

Oct 24, 2025 @ 12:00 PM Spyre Therapeutics Announces Poster Presentations ... Source: Spyre Therapeutics

Oct 14, 2025 @ 1:07 AM Spyre Therapeutics Announces Pricing of $275.0 Mil... Source: Spyre Therapeutics

Financials
	TTM	Q4 2025	FY 2025
Basic EPS
Diluted EPS
Revenue	$M	$M	$M
Gross Profit
Net Income / Loss	$-155.2M	$-62.53M	$-155.2M
Operating Income / Loss	$-209.56M	$-57.17M	$-209.56M
Cost of Revenue
Net Cash Flow	$-3.7M	$20.82M	$-3.7M
PE Ratio

Splits
Sep 08, 2023	1:25