Ticker Details
Spyre Therapeutics, Inc.
IPO Date:	April 4, 2016
Sector:	Healthcare
Industry:	Biotech
Market Cap:	$8.28B
Activated in VL:	True

Average Daily Range
Avg Daily Range:	$1.11 | 3.68%
Avg Daily Range (30 D):	$2.81 | 3.33%
Avg Daily Range (90 D):	$2.37 | 3.62%

Institutional Daily Volume
Avg Daily Volume:	.14M
Avg Daily Volume (30 D):	1.21M
Avg Daily Volume (90 D):	1M

Trade Size
Avg Trade Size (Sh.):	57
Avg Trade Size (Sh.) (30 D):	51
Avg Trade Size (Sh.) (90 D):	49

Institutional Trades
Total Institutional Trades:	1,468
Avg Institutional Trade:	$2.99M
Avg Institutional Trade (30 D):	$7.2M
Avg Institutional Trade (90 D):	$5.42M
Avg Institutional Trade Volume:	.08M
Avg Institutional Trades (Per Day):	2

Market Closing Trades
Avg Closing Trade:	$4.62M
Avg Closing Trade (30 D):	$22.58M
Avg Closing Trade (90 D):	$13.71M
Avg Closing Volume:	129.28K

News

Apr 15, 2026 @ 2:38 AM Spyre Therapeutics Announces Pricing of Upsized $4... Source: Not Specified

Apr 13, 2026 @ 8:46 PM Spyre Therapeutics Announces Proposed Public Offer... Source: Globe Newswire

Apr 13, 2026 @ 8:46 PM Spyre Therapeutics Announces Proposed Public Offer... Source: Not Specified

Apr 13, 2026 @ 11:00 AM Spyre Announces Potential Best-in-Class SPY001 Par... Source: Spyre Therapeutics, Inc.

Mar 19, 2026 @ 2:34 AM Signal or Noise: What VR Adviser's Spyre Theraputi... Source: Seena Hassouna

Financials
	TTM	Q4 2025	FY 2025
Basic EPS
Diluted EPS	$-.74
Revenue	$M	$M	$M
Gross Profit
Net Income / Loss	$-69.01M	$-62.53M	$-155.2M
Operating Income / Loss	$-45.64M	$-57.17M	$-209.56M
Cost of Revenue
Net Cash Flow	$11.46M	$20.82M	$-3.7M
PE Ratio

Splits
Sep 08, 2023	1:25