Basics Spruce Biosciences, Inc. IPO Date: October 9, 2020 Sector: Healthcare Industry: Biotech Market Cap: $83.49M Activated in VL: True Average Daily Range Avg Daily Range: $0.49 | 4.49% Avg Daily Range (30 D): $9.25 | 19.69% Avg Daily Range (90 D): $6.11 | 15.28% Institutional Daily Volume Avg Daily Volume: .51M Avg Daily Volume (30 D): .68M Avg Daily Volume (90 D): .33M Trade Size Avg Trade Size (Sh.): 208 Avg Trade Size (Sh.) (30 D): 20 Avg Trade Size (Sh.) (90 D): 29 Institutional Trades Total Inst.Trades: 66 Avg Inst. Trade: $1.99M Avg Inst. Trade (30 D): $2.45M Avg Inst. Trade (90 D): $2.45M Avg Inst. Trade Volume: .01M Avg Inst. Trades (Per Day): 2 Market Closing Trades Avg Closing Trade: $3.87M Avg Closing Trade (30 D): $2.54M Avg Closing Trade (90 D): $2.54M Avg Closing Volume: 7.66K     News Jan 9, 2025 @ 6:00 PM Rare Endocrinology and Metabolic Disorders Market ... Source: Delveinsight May 13, 2024 @ 9:10 PM Spruce Biosciences, Inc. (SPRB) Reports Q1 Loss, T... Source: Zacks Equity Research May 1, 2024 @ 11:55 AM Pfizer (PFE) Q1 Earnings and Revenues Beat Estimat... Source: Zacks Equity Research Mar 27, 2024 @ 4:00 PM Spruce Biosciences (SPRB) Upgraded to Buy: Here's ... Source: Zacks Equity Research Mar 21, 2024 @ 2:20 PM Spruce Biosciences (SPRB) Falls 86% in a Month: He... Source: Zacks Equity Research Financials   TTM Q1 2025 Q4 2024 Basic EPS $-28.14 $-.32 $-.57 Diluted EPS $-28.14 $-.32 $-.57 Revenue $ 1.3M $ M $ .7M Gross Profit $ $ $ Net Income / Loss $ -48.34M $ -14.04M $ -23.56M Operating Income / Loss $ -50.67M $ -14.49M $ -24.07M Cost of Revenue $ $ $ Net Cash Flow $ M $ M $ M PE Ratio     Splits Aug 07, 2025:   1:75