Ticker Details
Ionis Pharmaceuticals, Inc. Ionis Pharmaceuticals Inc is the RNA-targeted drug discovery and development company. Its broad pipeline consists of close to 32 drugs to treat a wide variety of diseases with an emphasis on cardiovascular, metabolic, severe, and rare diseases.
IPO Date:	December 22, 2015
Sector:	Healthcare
Industry:	Biotech
Market Cap:	$12.63B
Activated in VL:	True

Average Daily Range
Avg Daily Range:	$0.89 | 1.96%
Avg Daily Range (30 D):	$1.03 | 1.38%
Avg Daily Range (90 D):	$1.03 | 1.31%

Institutional Daily Volume
Avg Daily Volume:	1.21M
Avg Daily Volume (30 D):	1.83M
Avg Daily Volume (90 D):	1.76M

Trade Size
Avg Trade Size (Sh.):	82
Avg Trade Size (Sh.) (30 D):	54
Avg Trade Size (Sh.) (90 D):	59

Institutional Trades
Total Institutional Trades:	12,081
Avg Institutional Trade:	$2.9M
Avg Institutional Trade (30 D):	$6.24M
Avg Institutional Trade (90 D):	$6M
Avg Institutional Trade Volume:	.06M
Avg Institutional Trades (Per Day):	4

Market Closing Trades
Avg Closing Trade:	$6.89M
Avg Closing Trade (30 D):	$24.43M
Avg Closing Trade (90 D):	$21.77M
Avg Closing Volume:	147.1K

News

Apr 6, 2026 @ 12:00 PM Praxis Precision Medicines Announces Positive Resu... Source: Na

Mar 26, 2026 @ 5:47 PM Ionis Pharmaceuticals Repriced Drug Ahead Of Key F... Source: Vandana Singh

Mar 24, 2026 @ 7:07 PM When Insider Selling Is a Good Thing: 2 Stocks to ... Source: Thomas Hughes

Mar 20, 2026 @ 4:07 PM Biotech Stock Up 372% Gets Sold as New Pick Rises ... Source: Jonathan Ponciano

Feb 19, 2026 @ 8:30 AM Global Amyotrophic Lateral Sclerosis Therapeutics ... Source: Custom Market Insights

Financials
	TTM	Q4 2025	FY 2025
Basic EPS	$-2.38	$-1.41	$-2.38
Diluted EPS	$-2.38	$-1.41	$-2.38
Revenue	$943.71M	$203.33M	$943.71M
Gross Profit	$927.8M	$195.37M	$927.8M
Net Income / Loss	$-381.39M	$-229.39M	$-381.39M
Operating Income / Loss	$-381.68M	$-214.46M	$-381.68M
Cost of Revenue	$15.91M	$7.96M	$15.91M
Net Cash Flow	$129.48M	$33.96M	$129.48M
PE Ratio