Ticker Details
Upstream Bio, Inc. Common Stock
IPO Date:	October 11, 2024
Sector:	Healthcare
Industry:	Biotech
Market Cap:	$455.5M
Activated in VL:	True

Average Daily Range
Avg Daily Range:	$0.60 | 3.80%
Avg Daily Range (30 D):	$0.23 | 2.50%
Avg Daily Range (90 D):	$0.53 | 3.60%

Institutional Daily Volume
Avg Daily Volume:	.47M
Avg Daily Volume (30 D):	.45M
Avg Daily Volume (90 D):	.92M

Trade Size
Avg Trade Size (Sh.):	71
Avg Trade Size (Sh.) (30 D):	56
Avg Trade Size (Sh.) (90 D):	80

Institutional Trades
Total Institutional Trades:	452
Avg Institutional Trade:	$1.49M
Avg Institutional Trade (30 D):	$.93M
Avg Institutional Trade (90 D):	$1.27M
Avg Institutional Trade Volume:	.09M
Avg Institutional Trades (Per Day):	1

Market Closing Trades
Avg Closing Trade:	$1.7M
Avg Closing Trade (30 D):	$.78M
Avg Closing Trade (90 D):	$1.37M
Avg Closing Volume:	110.42K

News

Apr 23, 2026 @ 5:00 PM Chronic Obstructive Pulmonary Disease Clinical Tri... Source: Delveinsight

Apr 7, 2026 @ 5:00 PM Severe Asthma Clinical Trial Pipeline Appears Robu... Source: Delveinsight

Apr 7, 2026 @ 11:02 AM From Lungs To Nasal Polyps: Sanofi Finds Success W... Source: Vandana Singh

Mar 1, 2026 @ 2:45 PM Upstream Bio Presents Additional Analyses from the... Source: Upstream Bio, Inc.

Feb 26, 2026 @ 12:00 PM Upstream Bio to Present Additional Analyses from P... Source: Upstream Bio, Inc.

Financials
	TTM	Q4 2025	FY 2025
Basic EPS	$-.75	$-.78	$-2.66
Diluted EPS	$-.75	$-.78	$-2.66
Revenue	$1.03M	$.67M	$2.85M
Gross Profit
Net Income / Loss	$-40.59M	$-42.46M	$-143.44M
Operating Income / Loss	$-43.62M	$-46.17M	$-160.36M
Cost of Revenue
Net Cash Flow	$-4.85M	$29.41M	$-224.31M
PE Ratio