Ticker Details
Upstream Bio, Inc. Common Stock
IPO Date:	October 11, 2024
Sector:	Healthcare
Industry:	Biotech
Market Cap:	$436.63M
Activated in VL:	True

Average Daily Range
Avg Daily Range:	$0.66 | 3.96%
Avg Daily Range (30 D):	$1.16 | 5.26%
Avg Daily Range (90 D):	$0.97 | 4.04%

Institutional Daily Volume
Avg Daily Volume:	.43M
Avg Daily Volume (30 D):	1.51M
Avg Daily Volume (90 D):	.79M

Trade Size
Avg Trade Size (Sh.):	73
Avg Trade Size (Sh.) (30 D):	101
Avg Trade Size (Sh.) (90 D):	82

Institutional Trades
Total Institutional Trades:	391
Avg Institutional Trade:	$1.52M
Avg Institutional Trade (30 D):	$1.25M
Avg Institutional Trade (90 D):	$1.4M
Avg Institutional Trade Volume:	.08M
Avg Institutional Trades (Per Day):	2

Market Closing Trades
Avg Closing Trade:	$1.86M
Avg Closing Trade (30 D):	$1.64M
Avg Closing Trade (90 D):	$1.62M
Avg Closing Volume:	102.11K

News

Feb 10, 2026 @ 11:00 PM Upstream Bio to Host Webcast to Report Top-Line Re... Source: Na

Oct 31, 2025 @ 11:00 AM Upstream Bio to Participate in Upcoming November I... Source: Meggan Buckwell

Jun 15, 2025 @ 11:45 AM Translational Data Illustrate a Mechanism of Great... Source: Upstream Bio, Inc.

Jun 5, 2025 @ 11:00 AM Upstream Bio to Present Mechanistic Insights into ... Source: N/A

Financials
	TTM	Q2 2025	Q1 2025
Basic EPS	$-.63	$-.74	$-.51
Diluted EPS	$-.63	$-.74	$-.51
Revenue	$.68M	$.94M	$.57M
Gross Profit
Net Income / Loss	$-33.75M	$-39.97M	$-27.27M
Operating Income / Loss	$-37.83M	$-44.35M	$-32.01M
Cost of Revenue
Net Cash Flow	$26.71M	$-25.85M	$-254.58M
PE Ratio