Basics Upstream Bio, Inc. Common Stock IPO Date: October 11, 2024 Sector: Healthcare Industry: Biotech Market Cap: $1.08B Activated in VL: True Average Daily Range Avg Daily Range: $0.55 | 4.04% Avg Daily Range (30 D): $0.69 | 4.30% Avg Daily Range (90 D): $0.42 | 3.36% Institutional Daily Volume Avg Daily Volume: .3M Avg Daily Volume (30 D): .49M Avg Daily Volume (90 D): .37M Trade Size Avg Trade Size (Sh.): 67 Avg Trade Size (Sh.) (30 D): 72 Avg Trade Size (Sh.) (90 D): 65 Institutional Trades Total Inst.Trades: 118 Avg Inst. Trade: $1.75M Avg Inst. Trade (30 D): $.93M Avg Inst. Trade (90 D): $1.36M Avg Inst. Trade Volume: .12M Avg Inst. Trades (Per Day): 1 Market Closing Trades Avg Closing Trade: $2.35M Avg Closing Trade (30 D): $.77M Avg Closing Trade (90 D): $1.78M Avg Closing Volume: 162.49K     News Jun 15, 2025 @ 11:45 AM Translational Data Illustrate a Mechanism of Great... Source: Upstream Bio, Inc. Jun 5, 2025 @ 11:00 AM Upstream Bio to Present Mechanistic Insights into ... Source: N/A Financials   TTM Q2 2025 Q1 2025 Basic EPS $4.36 $-.74 $-.51 Diluted EPS $4.36 $-.74 $-.51 Revenue $ 2.72M $ .94M $ .57M Gross Profit $ $ $ Net Income / Loss $ -104.47M $ -39.97M $ -27.27M Operating Income / Loss $ -121.57M $ -44.35M $ -32.01M Cost of Revenue $ $ $ Net Cash Flow $ -1.68M $ -25.85M $ -254.58M PE Ratio 4.49