Ticker Details
Upstream Bio, Inc. Common Stock
IPO Date:	October 11, 2024
Sector:	Healthcare
Industry:	Biotech
Market Cap:	$567.06M
Activated in VL:	True

Average Daily Range
Avg Daily Range:	$0.62 | 3.88%
Avg Daily Range (30 D):	$0.27 | 3.10%
Avg Daily Range (90 D):	$0.78 | 3.90%

Institutional Daily Volume
Avg Daily Volume:	.46M
Avg Daily Volume (30 D):	.74M
Avg Daily Volume (90 D):	.91M

Trade Size
Avg Trade Size (Sh.):	71
Avg Trade Size (Sh.) (30 D):	66
Avg Trade Size (Sh.) (90 D):	79

Institutional Trades
Total Institutional Trades:	423
Avg Institutional Trade:	$1.53M
Avg Institutional Trade (30 D):	$1.64M
Avg Institutional Trade (90 D):	$1.48M
Avg Institutional Trade Volume:	.09M
Avg Institutional Trades (Per Day):	1

Market Closing Trades
Avg Closing Trade:	$1.8M
Avg Closing Trade (30 D):	$1.55M
Avg Closing Trade (90 D):	$1.76M
Avg Closing Volume:	113.79K

News

Apr 7, 2026 @ 5:00 PM Severe Asthma Clinical Trial Pipeline Appears Robu... Source: Delveinsight

Apr 7, 2026 @ 11:02 AM From Lungs To Nasal Polyps: Sanofi Finds Success W... Source: Vandana Singh

Mar 1, 2026 @ 2:45 PM Upstream Bio Presents Additional Analyses from the... Source: Upstream Bio, Inc.

Feb 26, 2026 @ 12:00 PM Upstream Bio to Present Additional Analyses from P... Source: Upstream Bio, Inc.

Feb 25, 2026 @ 12:00 PM Upstream Bio to Participate in Upcoming March Inve... Source: Not Specified

Financials
	TTM	Q4 2025	FY 2025
Basic EPS	$-2.66	$-.78	$-2.66
Diluted EPS	$-2.66	$-.78	$-2.66
Revenue	$2.85M	$.67M	$2.85M
Gross Profit
Net Income / Loss	$-143.44M	$-42.46M	$-143.44M
Operating Income / Loss	$-160.36M	$-46.17M	$-160.36M
Cost of Revenue
Net Cash Flow	$-224.31M	$29.41M	$-224.31M
PE Ratio